Journal article
Prospective follow-up of quality of life for participants undergoing risk-reducing salpingo-oophorectomy or ovarian cancer screening in GOG-0199: An NRG Oncology/GOG study
PL Mai, HQ Huang, LB Wenzel, PK Han, RP Moser, GC Rodriguez, J Boggess, TJ Rutherford, DE Cohn, ND Kauff, KA Phillips, K Wilkinson, RM Wenham, C Hamilton, MA Powell, JL Walker, MH Greene, ML Hensley
Gynecologic Oncology | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2020
Abstract
Background: Risk-reducing salpingo-oophorectomy (RRSO) and ovarian cancer screening (OCS) are management options for women at increased risk of ovarian cancer. Long-term effects of these interventions on quality of life (QOL) are not well understood. Methods: GOG-0199 is a prospective cohort study of women at increased ovarian cancer risk who chose either RRSO or OCS as their risk management intervention. At study entry, 6, 12, 24 and 60 months of follow-up, participants completed the QOL questionnaire, which included the Medical Outcome Study Short Form-36, the Impact of Events Scales, the Center for Epidemiological Studies Depression Scale, the State-Trait Anxiety Inventory, the Functional..
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Grants
Awarded by National Cancer Institute
Funding Acknowledgements
The research of Drs. Phuong L Mai and Mark H. Greene was supported by the Intramural Research Program of the US National Cancer Institute, and by support services contracts with Westat Inc., Contract #s HHSN261200109D, HHSN261200655004C and HHSN261201300003C. GOG-0199 was supported by NCI Grants No. CA 27469 to the Gynecologic Oncology Group (GOG) Administrative Office and Tissue Bank, No. CA37517 to the GOG Statistical and Data Center, and by NCI Community Clinical Oncology Program Grant No. CA101165 as well as NRG Oncology (1U10 CA180822) and NRG Operations (U10CA180868). Dr. Hensley is supported in part by the MSK Cancer Center Support Grant P30 CA008748. KAP is an Australian National BC Foundation Practitioner Fellow.